Hyperphagic mice

Author: tmki

August undefined, 2024

WebIn line, obese mice, after treatment with exogenous FGF-21, demonstrated an impairment of downstream FGF-21 molecular pathways, implying a resistant state. 23 One potential mechanism for this supposedly FGF-21 resistance or insensitivity may be the above mentioned downregulation of FGFR1. 22 Of course, further mechanistic studies are … Web31 jan. 2024 · Growth hormone has a role in determining mouse trabecular bone mass; its effect is gender-specific. first in vivo evidence that Zn-16 mRNA abundance correlates …

Chao Deng - Professor - University of Wollongong LinkedIn

Web7 mrt. 2011 · We sought to determine the involvement of phosphatidyl inositol 3-kinase (PI3K) and AMP-activated protein kinase (AMPK) in the estrogenic antagonism of the cannabinoid regulation of energy homeostasis. Food intake and body weight were evaluated in ovariectomized female guinea pigs treated s.c. with estradiol benzoate (EB) or its … WebPsychoneuroendocrinology Apr 2014. Abstract. Although second-generation antipsychotics induce severe weight gain and obesity, there is a lack of detailed knowledge about the progressive development of antipsychotic-induced obesity. This study examined the hypothalamic histamine H1 receptor and AMP-activated protein kinase (H1R-AMPK) … dom4j jar download java

Inducible Neuronal Inactivation of Sim1 in Adult Mice Causes ...

Web14 apr. 2024 · Genetically modified mouse models lacking MCH or having disrupted the MCH-R1 gene are lean, hyperphagic, and have elevated energy expenditure (Takase et al., 2014). On the other hand, transgenic mice overexpressing the MCH gene develop hyperphagia, mild obesity, and insulin resistance (Ludwig et al., 2001). Anorexigenic … Web27 okt. 2015 · Upon 4 wk of Rosi/HFD intervention, the obesity-resistant phenotype was completely reversed. Compared with WT/cTg, AKO/cTg mice became hyperphagic and … Web15 dec. 2024 · Cold-induced hyperphagia requires AgRP neuron activation in mice To maintain energy homeostasis during cold exposure, the increased energy demands of … put poznan ekonto

Oxytocin deficiency mediates hyperphagic obesity of Sim1

Hyperphagic mice

Phenotypic characterization of Adig null mice suggests roles for ...

Web25 okt. 2024 · Conditional knockout mice revealed that oxytocin secretion from the paraventricular hypothalamic nucleus suppresses hyperphagic obesity partly via … Web1 feb. 2024 · Summary Macrophages control inflammation in obese animals, and may also directly or indirectly regulate energy storage. In a genetic screen we identify a PDGF …

Did you know?

Web29 mrt. 2024 · Srisai D, Gillum MP, Panaro BL, Zhang XM, Kotchabhakdi N, Shulman GI, Ellacott KL, Cone RD. Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse. Endocrinology. 2011 Mar;152(3):890-902. doi: 10.1210/en.2010-0716. Epub 2011 Jan 14. WebObesity and Metabolic Syndrome in Circadian Clock Mutant Mice Fred W. Turek,1,3 Corinne Joshu,3,4* Akira Kohsaka,3,4* Emily Lin,3,4* Ganka Ivanova,2,4 Erin …

WebPLOS ONE April 15, 2014. Fructose accounts for 10% of daily calories in the American diet. Fructose, but not glucose, given intracerebroventricularly stimulates homeostatic feeding mechanisms ... WebHaploinsufficiency of the transcription factor gene Sim1 has been previously implicated in hyperphagic obesity in humans and mice. To investigate the relation between Sim1 dosage and hyperphagia, ...

Web16 feb. 2024 · This animal model was used to assess the molecular and biochemical consequences of hyperphagia-induced obesity on hepatic lipid metabolism. We analyzed … Web4 nov. 2014 · AdPLA-deficient ob/ob mice remain hyperphagic but lean, with increased energy expenditure, yet have ectopic triglyceride storage and insulin resistance.

Web5 okt. 2024 · An acknowledged experimental technique aiming for massive weight gain by inducing a hyperphagic state is the administration of gold thioglucose (GTG). 1,2 …

Web18 dec. 2024 · As a consequence of hyperphagic obesity, Arnt2 mutant mice develop diabetes, insulin resistance and hepatic steatosis. Arnt2 R74C homozygous mice show similarly increased food consumption to Sim1 +/− mice (10% and 15%, respectively) ( Tolson et al., 2010 , 2014 ), which display deficits in neuroendocrine hormones that … dom 4 pokojeWebJejunal anorectic NAEs are thought to add to the control of food intake via activation of PPARalpha and the vagus nerve. The fat-induced decrease may explain part of the hyperphagic effect of... put potato skins down garbage disposalWebThe autosomal recessive ob/ob mouse has a mutation in the leptin gene on chromosome 6. 59–61 Leptin is produced by white adipose tissue and has anorexic effects via action on … put poke gamesWeb21 nov. 2024 · Performed rodents handling and wet-lab to support multiple projects. Published one paper as the first author and two as a collaborator. ... (SL) are obese and hyperphagic. put poznan ekursyWebleptin-deﬁcient ob/ob hyperphagic mice decreased their body weight gain, fat-mass gain and reduced food intake [15,16]. These effects were associated with reduced hyperglycemia, plasma total cholesterol and alanine aminotransferase, suggesting also an improvement in the metabolic consequences of these obesogenic conditions. Moreover ... put poznan harmonogramWebSemantic Scholar extracted view of "Effects of diazoxide on insulin secretion and metabolic efficiency in the db/db mouse." by S. Lee. Skip to search form Skip to main content Skip to account menu. Semantic Scholar's Logo. Search 211,518,677 papers from all fields of science. Search ... put poznan put.poznan.pl elogin