Smoothelin

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August undefined, 2024

Web6 Feb 2013 · Of particular relevance, alternative splicing of the smoothelin gene generates at least two isoforms, being the short smoothelin-A isoform (59 kDa) specifically expressed into contractile visceral SMCs, whereas the long smoothelin-B isoform (110 kDa) is thought to be expressed only in adult contractile VSMCs , . Therefore, the detection of smoothelin … WebSmoothelin is a novel cytoskeletal protein that reacts with the 59 kDa and 100 kDa proteins corresponding to Smoothelin A and B, respectively, which are exclusively found in smooth muscle cells (SMC). Cells with SMC-like characteristics, such as myofibroblasts and myoepithelial cells, as well as skeletal and cardiac muscle do not contain ...

Expression of the smoothelin gene is mediated by alternative …

WebWe conducted global microarray, proteomic, and metabolic analyses to study the role of the progesterone receptor and its transcriptional regulator, smoothelin-like protein 1 (SMTNL1) in the adaptation of skeletal muscle to pregnancy. We demonstrate that pregnancy promotes fiber-type changes from an oxidative to glycolytic isoform in skeletal ... WebSmoothelin is a useful tool in the evaluation of atherosclerotic lesions. Liquid in buffer (PBS) with 0.1% sodium azide. Detect Smoothelin using this Anti-Smoothelin Antibody, clone … pakistan women vs thailand women

Smoothelin-B Deficiency Results in Reduced Arterial …

WebSmoothelin; Smoothelin cytoskeleton protein; NM_001284429.1 → NP_001271358.1 smoothelin isoform c. See identical proteins and their annotated locations for NP_001271358.1. Status: VALIDATED. Description Transcript Variant: This variant (5) contains an alternate exon in the 5' end and differs in the 3' UTR and coding sequence … Webwww.ncbi.nlm.nih.gov Web14 Apr 2024 · Smoothelin antibody, a marker of terminally differentiated smooth muscle, is useful in distinguishing muscularis propria (positive) from muscularis mucosa (negative, … summary of woman at point zero

Smoothelins and the Control of Muscle Contractility.

Anti-Smoothelin Antibody, clone R4A - Sigma-Aldrich

WebSmoothelin is another smooth muscle contraction protein that is present in human and pig bladder detrusor muscle. 41 Smoothelin is a cytoskeletal protein specifically expressed in differentiated SMCs and has been shown to co-localize with α-SM actin. Smooth muscle myosin heavy chains (SMHCs) are motor proteins that power smooth muscle contraction. Web7 Jun 2010 · Smoothelin immunohistochemistry is a useful adjunct for assessing muscularis propria invasion in bladder carcinoma. Aims: To prospectively evaluate the utility of smoothelin immunohistochemical expression for the evaluation of muscularis propria (MP) in diagnostic transurethral resection of bladder tumour (TURBT) specimens and … pakistan world cupWebSmooth muscle cells are important for the functions of the circulatory, genitourinary, respiratory, and digestive systems. Unlike skeletal and cardiac muscle cells, where cell differentiation is accompanied by the stable expression of muscle-specific genes, 1 2 SMCs display remarkable phenotypic plasticity and retain the capacity to reenter the cell cycle. 3 … summary of woke inc

"http://www.cellmarque.com/antibodies/CM/2117/Smoothelin_R4A " - Smoothelin

Smoothelin

WebSmoothelin is exclusively expressed in fully differentiated (contractile) SMCs. RNA and protein analyses reveal a broad species distribution of this protein. Cells with SMC-like … WebSmoothelin is a constituent of the smooth muscle cell (SMC) cytoskeleton. Antibodies directed to smoothelin are a useful tool to monitor SMC differentiation. Smoothelin is …

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Web22 Feb 2024 · Here, we describe the function of Smoothelin-like 2 (SMTNL2), a member of the smooth-muscle-related Smoothelin protein family, in apical cortex maturation. SMTNL2 is induced during development in multiple epithelial tissues and localizes to the apical and junctional actin cortex in intestinal and kidney epithelial cells. SMTNL2 deficiency leads ... http://www.bioon.com.cn/doc/showarticle.asp?newsid=112434

Web12 Apr 2024 · 平滑肌细胞分化特异性抗原(SMTN)重组蛋白说明书. Recombinant Smoothelin (SMTN) [ PROPERTIES ] Residues: Gln742~Arg906. Tags: Two N-terminal Tags, His-tag and GST-tag WebSmoothelin [R4A] is a mouse monoclonal antibody directed to the cytoskeletal component of smooth muscle cells (SMC) known as smoothelin. Smoothelin is exclusively expressed in fully differentiated …

Web18 Jan 2024 · In agreement, actin-dependent smooth muscle markers (-SMA, calponin, MYH11 and smoothelin) as well as levels of MLC phosphorylation and contraction in response to KCl did not change between genotypes, suggesting that the absence of CRP3 does not affect the actin cytoskeleton. PDGF-BB-dependent chemotaxis was lower in … Web19 Aug 2010 · Smoothelin is a specific and robust marker for distinction of muscularis propria and muscularis mucosae in the gastrointestinal tract. Aims: As tumour specimens and biopsy specimens become smaller, recognition of anatomical structures relevant for staging is increasingly challenging. So far no marker is known that reliably discriminates …

Web8 Dec 2005 · SMMHC and smoothelin expression, calculated as SMMHC/α-SMA or smoothelin/α-SMA, ie, as values representative of SMC differentiation level, was lower in restenotic lesions versus mildly stenotic plaques (P<0.05 for SMMHCs and P<0.01 for smoothelin), stable plaques (P<0.001 for both proteins), and erosions (P<0.05 for …

WebSmoothelin is another smooth muscle contraction protein that is present in human and pig bladder detrusor muscle. 41 Smoothelin is a cytoskeletal protein specifically expressed in … summary of women\u0027s rightsWeb3 Apr 2024 · The expression of caldesmon, α-SMA, calponin, MHC, and smoothelin increased on the 7th and 10th days in the smooth muscle-like cells compared with undifferentiated ADSCs. 10 days after differentiation, immunoluorescence staining showed that differentiated smooth muscle-like cells expressed calcineurin binding protein, ... pakistan won hockey world cupWebAnti-Smoothelin antibody [R4A] See all Smoothelin primary antibodies Description Mouse monoclonal [R4A] to Smoothelin Host species Mouse Specificity Reacts with the 59 kDa … summary of wolf brotherWeb4 Aug 2008 · Abstract. Background— Smoothelins are actin-binding proteins that are abundantly expressed in healthy visceral (smoothelin-A) and vascular (smoothelin-B) … pakistan world cup 2022Web21 Mar 2024 · Smoothelin is a specific marker for smooth muscle cells with contractile capacity which has not been widely studied in glomus lesions. in this study, glomic cells … summary of words on fireWebOverview Product name Anti-Smoothelin antibody [EPR20044] See all Smoothelin primary antibodies Description Rabbit monoclonal [EPR20044] to Smoothelin Host species Rabbit … summary of work experience什么意思WebSmoothelin is a smooth muscle-specific marker expressed only in terminally differentiated smooth muscle cells as part of the cytoskeleton. It is expressed normally in the smooth … summary of women in the bible